In a small bowl, combine rub ingredients. Rub all over the brisket, then cover and refrigerate overnight.

Preheat oven to 300°F.

Set brisket fat side up on large piece of foil and wrap tightly. Transfer to shallow roasting pan. Bake until tender, about 3 ½ - 4 hours.

For the BBQ sauce: Combine ingredients in a medium saucepan. Bring to a boil, uncovered, then lower to a simmer, until it reduces to a thickness of your liking, stirring occasionally.

Slice the brisket and serve hot or cold with BBQ sauce.